Senior Research Fellow

UCL • London, England, United Kingdom • £52.49k - £61.53k / year • 3w ago

About us

The mission of the UCL GOS Institute of Child Health is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education an d training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

An experienced senior research fellow is required for projects developing the next generation of therapies for children with blood and immune disorders, including CAR T cells for leukaemia. The postholder will design, generate and investigate strategies to improve CAR T cell and haematopoietic stem cell therapies in pre-clinical studies. There will be close working with university and hospital partners, and supervision of junior staff and students. Team working, aptitude and excellent communication and record keeping skills will be essential. The postholder will have skills for investigating gene editing of T cells/haematopoietic stem cells, including in humanised models. This is exciting opportunity in a rapidly emerging area of translational medicine. The post is funded by GOSHCC and will be appointed for 12m in the first instance with scope for extension.

About you

Expertise in human T cell and/or stem cell handling, culture, genome editing, flow cytometry, and functional assays. Skills for humanised models of adoptive therapy and stem cell engraftment. Experience in design and testing of genome editing tools.

Customer advert reference: B02-08400